Perfluorooctanoic acid is a synthetic, stable perfluorinated carboxylic acid and fluorosurfactant. It has been used in the manufacture of such prominent consumer goods as Teflon and Gore-Tex. Exposure to perfluorooctanoic acid (PFOA), a man made chemical used in the manufacture of some common household products, appears to be associated with cardiovascular disease and peripheral arterial disease in a study of 1,216 individuals, according to a report published Online First by Archives of Internal Medicine. Surveys have suggested that PFOA (widely used in the manufacture of products such as lubricants, polishes, paper and textile coatings, and food packaging) is detectable in the blood of more than 98 percent of the U.S. population. Some evidence has suggested that an association may be biologically plausible between PFOA exposure and cardiovascular disease (CVD), according to the study background.