In a new evolutionary proof of the old adage, 'we are what we eat', Cornell University scientists have found tantalizing evidence that a vegetarian diet has led to a mutation that — if they stray from a balanced omega-6 to omega-3 diet — may make people more susceptible to inflammation, and by association, increased risk of heart disease and colon cancer. The discovery, led by Drs. Tom Brenna, Kumar Kothapalli, and Alon Keinan provides the first evolutionary detective work that traces a higher frequency of a particular mutation to a primarily vegetarian population from Pune, India (about 70 percent), when compared to a traditional meat-eating American population, made up of mostly Kansans (less than 20 percent). It appears in the early online edition of the journal Molecular Biology and Evolution.